Evaluation of iron overload

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Iron overload.

Dietary copper in the U.S. often is lower than that proved insufficient for men and women under controlled conditions. Iron overload can have adverse effects on copper nutriture and can produce cardiac disease in people. The hypothesis that iron can interfere with copper utilization to produce adverse effects related to cardiovascular function was tested. Rats were fed a diet high in iron and m...

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Iron Deficiency and Iron Overload.

Iron is essential to most, if not all, living organisms, and the higher animals and man have employed it for many purposes essential to life. The readiness with which iron undergoes oxidation and reduction is utilized in many of the enzymes of electron transport, and in a number of other enzymes whose function is not understood. Furthermore, the combination of iron with porphyrin and protein le...

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Hydrophilic Phytochelators in Iron Overload Condition

Background: Iron overload can cause many complications and damage many organs as well as physiologic functions. Consumption of phetochemicals and flavonoids with iron chelating ability, instead of synthetic iron chelators, can be less harmful and more effective. The aim of this review is to investigate hydrophilic phytochelators in iron overload condition. Methods: In this review, the possible ...

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Assessment of Pancreatic Iron Overload in Transfusion Dependent Thalassemic Patients

Advances in the management of transfusion dependent thalassemic patients have improved the survival of these patients. The most important consequence of repeated and frequent transfusions is iron accumulation in vital organs. The magnetic resonance imaging (MRI) is a non-invasive and valid technique for the estimation of iron stores. Despite multiple studies about cardiac and liver MRI T2*, the...

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Iron-overload myopathy.

A 66-year-old male patient presented with a 4-month history of progressive muscle weakness. Twelve years prior to presentation he was evaluated for fatigue, weight loss, new-onset diabetes and elevated liver enzymes and was diagnosed with hereditary hemochromatosis, homozygous for the C282Y mutation in the HFE gene. His total iron at diagnosis was 137 mcg/dL; iron binding capacity, 149 mcg/dL; ...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2004

ISSN: 0007-1048

DOI: 10.1111/j.1365-2141.2004.04838.x